Permatex® does not recommend the use of any anti-seize product on wheel studs. Many people have used anti-seize for this applications, however, there is the potential for over-torqueing and therefore, higher clamp loads and potentially dangerous bolt stretch. Because of the lubricity of anti-seize, there is a tendency to over-tighten because of the ease with which the nut will bear down on the lug. For this reason, even if you try to torque the nuts to factory specs, the clamp load may become too high depending on the type of bolt, size and manufacturer.
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